This is not a traditional job — you'll draw on your hands-on experience in genomics, NGS analysis, or computational biology to evaluate AI-generated content and provide feedback that helps AI reason like a practicing computational biologist or bioinformatics scientist.

This is an ongoing, project-based opportunity you can take on alongside your current role.

• Use your domain expertise to create expert-level bioinformatics problems and scenarios grounded in real pipeline design, sequence analysis, and research workflows.
• Review and evaluate AI-generated responses for technical accuracy, reproducibility, and alignment with how the work is actually done.
• Provide structured written feedback to help improve AI model performance.

Ideal candidates meet all three of the following:

• Industry/research experience — a track record of first-author publications and ownership of non-trivial bioinformatics pipelines that frontier AI models cannot reproduce.

• Degree — PhD in Computational Biology, Bioinformatics, Genomics, or a comparable quantitative/life sciences discipline. An MS paired with strong industry experience also qualifies.

• Sub-domain depth — demonstrated expertise in one of the following areas:

  • NGS/genomics pipelines (BWA, GATK, samtools) and sequence analysis (BLAST, Biopython).

  • Statistical genetics.

  • Structural biology (PyMOL, AlphaFold).

Candidates who meet at least 2 of the 3 qualifications above are also encouraged to apply.

Additional qualifications (not required, but strengthen your application)

• Proficiency with R/Bioconductor and other standard bioinformatics or computational biology software environments.

• Experience owning end-to-end genomics or NGS/sequencing pipelines in an academic or industry research setting.

Required for all applicants

• Must have US work authorization.

• Strong written communication and attention to detail.

• Ability to explain complex biological concepts clearly.

• Ability to work independently in a remote, asynchronous environment.

Work arrangement: Fully remote

• F-1 students who are eligible for CPT or OPT may be eligible for projects on Handshake AI. Work with your Designated School Official to determine your eligibility.  If your school requires a CPT course, Handshake AI may not meet your school’s requirements. STEM OPT is not supported. See our Help Center article for more information on what types of work authorizations are supported on Handshake AI.

• Depending on the project.